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ea0026p237 | Pituitary | ECE2011

Quality of life is impaired in association with the need for prolonged postoperative therapy by somatostatin analogs in patients with acromegaly

Postma M R , Netea-Maier R T , van den Berg G , Homan J , Sluiter W J , van den Bergh A C M , Wolffenbuttel B H R , Hermus A R M M , van Beek A P

Objective: To assess the influence of use of long-acting somatostatin analogs on long-term health-related quality of life (HR-QoL) in relation to disease control in patients surgically-treated for acromegaly.Design: Cross-sectional study in two University Medical Centers in The Netherlands.Patients: One hundred and eight patients (47 m/61 f, mean age 54±11 years) with a minimal follow up period of 1 year after pituitary surger...

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ea0026p255 | Pituitary | ECE2011

Quality of life and cortisol diurnal rhythm after 3 months of medical treatment for Cushing’s disease

van der Pas R , de Bruin C , Pereira A , Romijn J , Netea R , Hermus A , Zelissen P , de Jong F , van der Lelij A , de Herder W , Webb S , Lamberts S , Hofland L , Feelders R

Introduction: Cushings disease (CD) is characterized by various symptoms, amongst which fatigue, muscle weakness and depression. The chronic state of hypercortisolism severely impairs quality of life (QoL). In addition, the physiological cortisol diurnal rhythm (CDR) is disturbed in CD. Transsphenoidal surgery is the primary treatment for CD, but long-term remission rates are disappointing. We performed a prospective trial in which stepwise medical treatment was applied ...

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Endocrine Abstracts

Quality of life is impaired in association with the need for prolonged postoperative therapy by somatostatin analogs in patients with acromegaly

Quality of life and cortisol diurnal rhythm after 3 months of medical treatment for Cushing’s disease

BiosciAbstracts